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Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization

BACKGROUND: Fluorescence in situ Hybridization (FISH) utilizes peptide nucleic acid (PNA) probes to identify specific DNA sequences. Traditional techniques have required the heat denaturing of the DNA in formamide followed by multiple hours at moderated temperatures to allow the probe to hybridize t...

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Detalles Bibliográficos
Autores principales:	Genet, Matthew D, Cartwright, Ian M, Kato, Takamitsu A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852893/ https://www.ncbi.nlm.nih.gov/pubmed/24103162 http://dx.doi.org/10.1186/1755-8166-6-42

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