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The Sec63p J-Domain Is Required for ERAD of Soluble Proteins in Yeast
How misfolded proteins are exported from the ER to the cytosol for degradation (ER-associated Degradation, ERAD) and which proteins are participating in this process is not understood. Several studies using a single, leaky mutant indicated that Sec63p might be involved in ERAD. More recently, Sec63p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852996/ https://www.ncbi.nlm.nih.gov/pubmed/24324744 http://dx.doi.org/10.1371/journal.pone.0082058 |