Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

BACKGROUND: Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation. We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, with important implications for lung inflammation and COPD pathogenesis. METHODS:...

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Detalles Bibliográficos
Autores principales: Hoffmann, Roland F, Zarrintan, Sina, Brandenburg, Simone M, Kol, Arjan, de Bruin, Harold G, Jafari, Shabnam, Dijk, Freark, Kalicharan, Dharamdajal, Kelders, Marco, Gosker, Harry R, ten Hacken, Nick HT, van der Want, Johannes J, van Oosterhout, Antoon JM, Heijink, Irene H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852998/
https://www.ncbi.nlm.nih.gov/pubmed/24088173
http://dx.doi.org/10.1186/1465-9921-14-97

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