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HCS-Neurons: identifying phenotypic changes in multi-neuron images upon drug treatments of high-content screening

BACKGROUND: High-content screening (HCS) has become a powerful tool for drug discovery. However, the discovery of drugs targeting neurons is still hampered by the inability to accurately identify and quantify the phenotypic changes of multiple neurons in a single image (named multi-neuron image) of...

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Detalles Bibliográficos
Autores principales:	Charoenkwan, Phasit, Hwang, Eric, Cutler, Robert W, Lee, Hua-Chin, Ko, Li-Wei, Huang, Hui-Ling, Ho, Shinn-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853092/ https://www.ncbi.nlm.nih.gov/pubmed/24564437 http://dx.doi.org/10.1186/1471-2105-14-S16-S12

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