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Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2 gene
BACKGROUND: Chromosomal instability is a hallmark of human cancer caused by errors in mitotic control and chromosome segregation. STAG2 encodes a subunit of the cohesion complex that participates in mitotic chromatid separation and was recently found to show low expression and inactivating mutations...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853135/ https://www.ncbi.nlm.nih.gov/pubmed/24088605 http://dx.doi.org/10.1186/1471-2350-14-102 |