Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation

BACKGROUND: Receptors for advanced glycation end-products (RAGE) are cell surface receptors prominently expressed by lung epithelium. Previous research demonstrated that over-expression of RAGE by murine alveolar epithelial cells during embryogenesis caused severe lung hypoplasia and neonatal lethal...

Descripción completa

Detalles Bibliográficos
Autores principales: Winden, Duane R, Ferguson, Nicholas T, Bukey, Benjamin R, Geyer, Alexander J, Wright, Alex J, Jergensen, Zac R, Robinson, Adam B, Stogsdill, Jeffrey A, Reynolds, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853184/
https://www.ncbi.nlm.nih.gov/pubmed/24134692
http://dx.doi.org/10.1186/1465-9921-14-108

Ejemplares similares

Ejemplares similares