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20-Hydroxyeicosatetraenoic Acid Contributes to the Inhibition of K+ Channel Activity and Vasoconstrictor Response to Angiotensin II in Rat Renal Microvessels

The present study examined whether 20-hydroxyeicosatetraenoic acid (HETE) contributes to the vasoconstrictor effect of angiotensin II (ANG II) in renal microvessels by preventing activation of the large conductance Ca(2+)-activated K(+) channel (K(Ca)) in vascular smooth muscle (VSM) cells. ANG II i...

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Detalles Bibliográficos
Autores principales:	Fan, Fan, Sun, Cheng-Wen, Maier, Kristopher G., Williams, Jan M., Pabbidi, Malikarjuna R., Didion, Sean P., Falck, John R., Zhuo, Jialong, Roman, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853207/ https://www.ncbi.nlm.nih.gov/pubmed/24324797 http://dx.doi.org/10.1371/journal.pone.0082482

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