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12/15-Lipoxygenase Contributes to Platelet-derived Growth Factor-induced Activation of Signal Transducer and Activator of Transcription 3

We showed previously that the small molecule indirubin-3′-monoxime (I3MO) prevents vascular smooth muscle cell (VSMC) proliferation by selectively inhibiting signal transducer and activator of transcription 3 (STAT3). Looking for the underlying upstream molecular mechanism, we here reveal the import...

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Detalles Bibliográficos
Autores principales:	Blažević, Tina, Schwaiberger, Andrea V., Schreiner, Cornelia E., Schachner, Daniel, Schaible, Anja M., Grojer, Christoph S., Atanasov, Atanas G., Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853304/ https://www.ncbi.nlm.nih.gov/pubmed/24165129 http://dx.doi.org/10.1074/jbc.M113.489013

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