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Pathway-based drug repositioning using causal inference
BACKGROUND: Recent in vivo studies showed new hopes of drug repositioning through causality inference from drugs to disease. Inspired by their success, here we present an in silico method for building a causal network (CauseNet) between drugs and diseases, in an attempt to systematically identify ne...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853312/ https://www.ncbi.nlm.nih.gov/pubmed/24564553 http://dx.doi.org/10.1186/1471-2105-14-S16-S3 |