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Pathway-based drug repositioning using causal inference

BACKGROUND: Recent in vivo studies showed new hopes of drug repositioning through causality inference from drugs to disease. Inspired by their success, here we present an in silico method for building a causal network (CauseNet) between drugs and diseases, in an attempt to systematically identify ne...

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Detalles Bibliográficos
Autores principales: Li, Jiao, Lu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853312/
https://www.ncbi.nlm.nih.gov/pubmed/24564553
http://dx.doi.org/10.1186/1471-2105-14-S16-S3