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Secretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia coli via a modified Sec-dependent transporter construct

BACKGROUND: Interleukin-10 homologues encoded by Herpes viruses such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) hold interesting structural and biological characteristics compared to human interleukin-10 (hIL-10) that render these proteins promising candidates for therapeutic appli...

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Detalles Bibliográficos
Autores principales:	Förster, Sarah, Brandt, Manuela, Mottok, Dorothea S, Zschüttig, Anke, Zimmermann, Kurt, Blattner, Frederick R, Gunzer, Florian, Pöhlmann, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853369/ https://www.ncbi.nlm.nih.gov/pubmed/24093616 http://dx.doi.org/10.1186/1472-6750-13-82

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