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Higher Expression of Receptor Tyrosine Kinase Axl, and Differential Expression of its Ligand, Gas6, Predict Poor Survival in Lung Adenocarcinoma Patients

BACKGROUND: Downstream activation through receptor tyrosine kinases (RTKs) plays important roles in carcinogenesis. In this study, we assessed the clinical involvement of Axl, an RTK, and its ligand, Gas6, in surgically treated lung adenocarcinoma. METHODS: Axl and Gas6 mRNA and protein expression l...

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Detalles Bibliográficos
Autores principales:	Ishikawa, Masashi, Sonobe, Makoto, Nakayama, Ei, Kobayashi, Masashi, Kikuchi, Ryutaro, Kitamura, Jiro, Imamura, Naoto, Date, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Translational Research and Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853411/ https://www.ncbi.nlm.nih.gov/pubmed/23242819 http://dx.doi.org/10.1245/s10434-012-2795-3

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