Cargando…

Higher Expression of Receptor Tyrosine Kinase Axl, and Differential Expression of its Ligand, Gas6, Predict Poor Survival in Lung Adenocarcinoma Patients

BACKGROUND: Downstream activation through receptor tyrosine kinases (RTKs) plays important roles in carcinogenesis. In this study, we assessed the clinical involvement of Axl, an RTK, and its ligand, Gas6, in surgically treated lung adenocarcinoma. METHODS: Axl and Gas6 mRNA and protein expression l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ishikawa, Masashi, Sonobe, Makoto, Nakayama, Ei, Kobayashi, Masashi, Kikuchi, Ryutaro, Kitamura, Jiro, Imamura, Naoto, Date, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Translational Research and Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853411/ https://www.ncbi.nlm.nih.gov/pubmed/23242819 http://dx.doi.org/10.1245/s10434-012-2795-3

Ejemplares similares

Expression of the GLI family genes is associated with tumor progression in advanced lung adenocarcinoma
por: Ishikawa, Masashi, et al.
Publicado: (2014)

Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours
por: Green, J, et al.
Publicado: (2006)

Axl receptor tyrosine kinase is a potential therapeutic target in renal cell carcinoma
por: Yu, H, et al.
Publicado: (2015)

Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma
por: Dantas-Barbosa, Carmela, et al.
Publicado: (2017)

Clinicopathological Significance of BMP7 Expression in Esophageal Squamous Cell Carcinoma
por: Megumi, Koichi, et al.
Publicado: (2011)

High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett’s Esophagus and Adenocarcinoma
por: Fisher, Oliver M., et al.
Publicado: (2014)

Inhibition of p600 Expression Suppresses Both Invasiveness and Anoikis Resistance of Gastric Cancer
por: Sakai, Hiroshi, et al.
Publicado: (2011)

MicroRNA Expression as a Predictive Marker for Gemcitabine Response after Surgical Resection of Pancreatic Cancer
por: Ohuchida, Kenoki, et al.
Publicado: (2011)

Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases
por: Olino, Kelly, et al.
Publicado: (2011)

Expression of B7-H3, a Potential Factor of Tumor Immune Evasion in Combination with the Number of Regulatory T Cells, Affects Against Recurrence-Free Survival in Breast Cancer Patients
por: Maeda, N., et al.
Publicado: (2014)

Comparison of programmed death-ligand 1 protein expression between primary and metastatic lesions in patients with lung cancer
por: Moutafi, Myrto K, et al.
Publicado: (2021)

Glucose-6-phosphate dehydrogenase correlates with tumor immune activity and programmed death ligand-1 expression in Merkel cell carcinoma
por: Nakamura, Motoki, et al.
Publicado: (2020)

Enhanced Detection of Early Hepatocellular Carcinoma by Serum SELDI-TOF Proteomic Signature Combined with Alpha-Fetoprotein Marker
por: Chen, Lei, et al.
Publicado: (2010)

Radioimmunotherapy Improves Survival of Rats with Microscopic Liver Metastases of Colorectal Origin
por: de Jong, Gabie M., et al.
Publicado: (2009)

KRAS Mutation in Colon Cancer: A Marker of Resistance to EGFR-I Therapy
por: Siddiqui, Ahmad D., et al.
Publicado: (2009)

Alterations of Circulating Bone Marrow–Derived VEGFR-2(+) Progenitor Cells in Isolated Limb Perfusion With or Without rhTNF-α
por: Nowak, Kai, et al.
Publicado: (2012)

Quantitative X-ray Computed Tomography Peritoneography in Malignant Peritoneal Mesothelioma Patients Receiving Intraperitoneal Chemotherapy
por: Leinwand, Joshua C., et al.
Publicado: (2013)

KRAS and BRAF Mutations in 203 Esophageal Squamous Cell Carcinomas: Pyrosequencing Technology and Literature Review
por: Shigaki, Hironobu, et al.
Publicado: (2012)

Lumican and Versican Are Associated with Good Outcome in Stage II and III Colon Cancer
por: de Wit, Meike, et al.
Publicado: (2012)

Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse
por: Carpinteri, Sandra, et al.
Publicado: (2015)

In Vivo Feasibility of Electrostatic Precipitation as an Adjunct to Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC)
por: Kakchekeeva, Tinatin, et al.
Publicado: (2016)

Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer
por: Mokutani, Yukako, et al.
Publicado: (2016)

Metastasectomy for Tumor-Infiltrating Lymphocytes: An Emerging Operative Indication in Surgical Oncology
por: Crompton, Joseph G., et al.
Publicado: (2017)

Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography Results in Negative Surgical Margins and Decreased Local Recurrence in an Orthotopic Mouse Model of Osteosarcoma
por: Mahjoub, Adel, et al.
Publicado: (2018)

MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes
por: Fraune, Christoph, et al.
Publicado: (2020)

Establishment and Characterization of Two Novel Cholangiocarcinoma Cell Lines
por: Zhang, Yanhua, et al.
Publicado: (2019)

Nicaraven Attenuates Postoperative Systemic Inflammatory Responses-Induced Tumor Metastasis
por: Zhang, Xu, et al.
Publicado: (2019)

Lymph Node Positivity in One-Step Nucleic Acid Amplification is a Prognostic Factor for Postoperative Cancer Recurrence in Patients with Stage II Colorectal Cancer: A Prospective, Multicenter Study
por: Itabashi, Michio, et al.
Publicado: (2019)

Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
por: Enblad, Malin, et al.
Publicado: (2019)

Distal Gastrectomy with Billroth II Reconstruction is Associated with Oralization of Gut Microbiome and Intestinal Inflammation: A Proof-of-Concept Study
por: Horvath, Angela, et al.
Publicado: (2020)

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
por: Brenig, Robert, et al.
Publicado: (2019)

Enhanced B7-H4 expression in gliomas with low PD-L1 expression identifies super-cold tumors
por: Chen, Di, et al.
Publicado: (2020)

Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma
por: Haddad, Robert I, et al.
Publicado: (2022)

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus
por: Vincent, Fabien B, et al.
Publicado: (2020)

Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity
por: Reches, Adi, et al.
Publicado: (2020)

Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up
por: Schoindre, Yoland, et al.
Publicado: (2014)

Higher baseline levels of CSF inflammation increase risk of incident mild cognitive impairment and Alzheimer's disease dementia
por: Contreras, Joey A., et al.
Publicado: (2022)

Chronic Lung Injury by Constitutive Expression of Activation-Induced Cytidine Deaminase Leads to Focal Mucous Cell Metaplasia and Cancer
por: Kitamura, Jiro, et al.
Publicado: (2015)

The Receptor Tyrosine Kinase AXL in Cancer Progression
por: Rankin, Erinn B., et al.
Publicado: (2016)

PD-L1 gene amplification and focality: relationship with protein expression
por: Jardim, Denis Leonardo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1tvo3ke7763a4n2arfr7rp7mh8