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Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases

ABSTRACT: Tufted angioma, first recognized in Japanese literature as “Angioblastoma of Nagakawa”, is a rare benign vascular tumour with a variable clinical presentation. It commonly manifests as a macule, papule or nodule in infancy or childhood in the region of the upper trunk and neck. Here in we...

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Autores principales: Mittal, Ruchi, Tripathy, Devjyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853550/
https://www.ncbi.nlm.nih.gov/pubmed/24044498
http://dx.doi.org/10.1186/1746-1596-8-153
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author Mittal, Ruchi
Tripathy, Devjyoti
author_facet Mittal, Ruchi
Tripathy, Devjyoti
author_sort Mittal, Ruchi
collection PubMed
description ABSTRACT: Tufted angioma, first recognized in Japanese literature as “Angioblastoma of Nagakawa”, is a rare benign vascular tumour with a variable clinical presentation. It commonly manifests as a macule, papule or nodule in infancy or childhood in the region of the upper trunk and neck. Here in we report two cases of this rare progressive angioma as lesions of the eyelid in adults. Tufted angioma has a classical “cannon ball” like appearance of vascular tufts on histopathology. Immunohistochemical staining with actin highlights the spindly stromal cells surrounding the capillaries. Complete physical examination and haematological work up is recommended in patients with tufted angioma to exclude rare association of port wine stain and Kasabach-Merritt syndrome with this rare entity. To the best of our knowledge, our cases illustrate the first case report of tufted angioma presenting as an eyelid lesion. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1230909536950947.
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spelling pubmed-38535502013-12-07 Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases Mittal, Ruchi Tripathy, Devjyoti Diagn Pathol Case Report ABSTRACT: Tufted angioma, first recognized in Japanese literature as “Angioblastoma of Nagakawa”, is a rare benign vascular tumour with a variable clinical presentation. It commonly manifests as a macule, papule or nodule in infancy or childhood in the region of the upper trunk and neck. Here in we report two cases of this rare progressive angioma as lesions of the eyelid in adults. Tufted angioma has a classical “cannon ball” like appearance of vascular tufts on histopathology. Immunohistochemical staining with actin highlights the spindly stromal cells surrounding the capillaries. Complete physical examination and haematological work up is recommended in patients with tufted angioma to exclude rare association of port wine stain and Kasabach-Merritt syndrome with this rare entity. To the best of our knowledge, our cases illustrate the first case report of tufted angioma presenting as an eyelid lesion. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1230909536950947. BioMed Central 2013-09-17 /pmc/articles/PMC3853550/ /pubmed/24044498 http://dx.doi.org/10.1186/1746-1596-8-153 Text en Copyright © 2013 Mittal and Tripathy; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mittal, Ruchi
Tripathy, Devjyoti
Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title_full Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title_fullStr Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title_full_unstemmed Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title_short Tufted angioma (Angioblastoma) of eyelid in adults-report of two cases
title_sort tufted angioma (angioblastoma) of eyelid in adults-report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853550/
https://www.ncbi.nlm.nih.gov/pubmed/24044498
http://dx.doi.org/10.1186/1746-1596-8-153
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