New Diterpenoids from Soft Coral Sarcophyton ehrenbergi

Continuing chemical investigation on the acetone extracts of the soft coral Sarcophyton ehrenbergi collected off the coast of San-hsian-tai, Taitong County, Taiwan led to the isolation of two new diterpenoids, ehrenbergol C and acetyl ehrenberoxide B (1 and 2). The structures of these isolated metab...

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Autores principales: Wang, Shang-Kwei, Hsieh, Mu-Keng, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853730/
https://www.ncbi.nlm.nih.gov/pubmed/24177676
http://dx.doi.org/10.3390/md11114318
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author Wang, Shang-Kwei
Hsieh, Mu-Keng
Duh, Chang-Yih
author_facet Wang, Shang-Kwei
Hsieh, Mu-Keng
Duh, Chang-Yih
author_sort Wang, Shang-Kwei
collection PubMed
description Continuing chemical investigation on the acetone extracts of the soft coral Sarcophyton ehrenbergi collected off the coast of San-hsian-tai, Taitong County, Taiwan led to the isolation of two new diterpenoids, ehrenbergol C and acetyl ehrenberoxide B (1 and 2). The structures of these isolated metabolites were elucidated through extensive spectroscopic analyses. Moreover, in vitro tests show that compounds 1 and 2 displayed antiviral activity towards human cytomegalovirus, with EC(50) of 20 and 8.0 µg/mL, respectively.
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spelling pubmed-38537302013-12-06 New Diterpenoids from Soft Coral Sarcophyton ehrenbergi Wang, Shang-Kwei Hsieh, Mu-Keng Duh, Chang-Yih Mar Drugs Article Continuing chemical investigation on the acetone extracts of the soft coral Sarcophyton ehrenbergi collected off the coast of San-hsian-tai, Taitong County, Taiwan led to the isolation of two new diterpenoids, ehrenbergol C and acetyl ehrenberoxide B (1 and 2). The structures of these isolated metabolites were elucidated through extensive spectroscopic analyses. Moreover, in vitro tests show that compounds 1 and 2 displayed antiviral activity towards human cytomegalovirus, with EC(50) of 20 and 8.0 µg/mL, respectively. MDPI 2013-10-30 /pmc/articles/PMC3853730/ /pubmed/24177676 http://dx.doi.org/10.3390/md11114318 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Shang-Kwei
Hsieh, Mu-Keng
Duh, Chang-Yih
New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title_full New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title_fullStr New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title_full_unstemmed New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title_short New Diterpenoids from Soft Coral Sarcophyton ehrenbergi
title_sort new diterpenoids from soft coral sarcophyton ehrenbergi
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853730/
https://www.ncbi.nlm.nih.gov/pubmed/24177676
http://dx.doi.org/10.3390/md11114318
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