Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.

A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Tsung-Hung, Lu, Mei-Chin, Chang, Yu-Chia, Su, Yin-Di, Chen, Yu-Hsin, Lin, Nai-Cheng, Fang, Lee-Shing, Wu, Yang-Chang, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853747/
https://www.ncbi.nlm.nih.gov/pubmed/24240980
http://dx.doi.org/10.3390/md11114585
Descripción
Sumario:A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.

Ejemplares similares