Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.

A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data wi...

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Autores principales: Chen, Tsung-Hung, Lu, Mei-Chin, Chang, Yu-Chia, Su, Yin-Di, Chen, Yu-Hsin, Lin, Nai-Cheng, Fang, Lee-Shing, Wu, Yang-Chang, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853747/
https://www.ncbi.nlm.nih.gov/pubmed/24240980
http://dx.doi.org/10.3390/md11114585
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author Chen, Tsung-Hung
Lu, Mei-Chin
Chang, Yu-Chia
Su, Yin-Di
Chen, Yu-Hsin
Lin, Nai-Cheng
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
author_facet Chen, Tsung-Hung
Lu, Mei-Chin
Chang, Yu-Chia
Su, Yin-Di
Chen, Yu-Hsin
Lin, Nai-Cheng
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
author_sort Chen, Tsung-Hung
collection PubMed
description A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.
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spelling pubmed-38537472013-12-06 Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp. Chen, Tsung-Hung Lu, Mei-Chin Chang, Yu-Chia Su, Yin-Di Chen, Yu-Hsin Lin, Nai-Cheng Fang, Lee-Shing Wu, Yang-Chang Sung, Ping-Jyun Mar Drugs Article A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells. MDPI 2013-11-14 /pmc/articles/PMC3853747/ /pubmed/24240980 http://dx.doi.org/10.3390/md11114585 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Chen, Tsung-Hung
Lu, Mei-Chin
Chang, Yu-Chia
Su, Yin-Di
Chen, Yu-Hsin
Lin, Nai-Cheng
Fang, Lee-Shing
Wu, Yang-Chang
Sung, Ping-Jyun
Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title_full Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title_fullStr Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title_full_unstemmed Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title_short Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
title_sort discovery of new eunicellin-based diterpenoids from a formosan soft coral cladiella sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853747/
https://www.ncbi.nlm.nih.gov/pubmed/24240980
http://dx.doi.org/10.3390/md11114585
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