LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/stat3/akt pathway

BACKGROUND: Gankyrin has shown to be overexpressed in human liver cancers and plays a complex role in hepatocarcinogenesis. Panobinostat (LBH589), a new hydroxamic acid-derived histone deacetylase inhibitor has shown promising anticancer effects recently. Here, we investigated the potential of LBH58...

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Detalles Bibliográficos
Autores principales: Song, Xuan, Wang, Jiabei, Zheng, Tongsen, Song, Ruipeng, Liang, Yingjian, Bhatta, Nishant, Yin, Dalong, Pan, Shangha, Liu, Jiaren, Jiang, Hongchi, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853770/
https://www.ncbi.nlm.nih.gov/pubmed/24093956
http://dx.doi.org/10.1186/1476-4598-12-114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853770/
https://www.ncbi.nlm.nih.gov/pubmed/24093956
http://dx.doi.org/10.1186/1476-4598-12-114

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