Cargando…

Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury

Radiofrequency (RF) is often used as a supplementary and alternative method to alleviate pain for chronic tendinopathy. Whether or how it would work for acute tendon injury is not addressed in the literatures. Through detailed pain and gait monitoring, we hypothesized that collagenase-induce acute t...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Yun-Pu, Chang, Chi-Wen, Lee, Jung-Shun, Liang, Jen-I, Hsieh, Tsung-Hsun, Yeh, Ming-Long, Sze, Chun-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853797/
https://www.ncbi.nlm.nih.gov/pubmed/24348697
http://dx.doi.org/10.1155/2013/402692
_version_ 1782294697665888256
author Tsai, Yun-Pu
Chang, Chi-Wen
Lee, Jung-Shun
Liang, Jen-I
Hsieh, Tsung-Hsun
Yeh, Ming-Long
Sze, Chun-I
author_facet Tsai, Yun-Pu
Chang, Chi-Wen
Lee, Jung-Shun
Liang, Jen-I
Hsieh, Tsung-Hsun
Yeh, Ming-Long
Sze, Chun-I
author_sort Tsai, Yun-Pu
collection PubMed
description Radiofrequency (RF) is often used as a supplementary and alternative method to alleviate pain for chronic tendinopathy. Whether or how it would work for acute tendon injury is not addressed in the literatures. Through detailed pain and gait monitoring, we hypothesized that collagenase-induce acute tendinopathy model may be able to answer these questions. Gait parameters, including time, distance, and range of motion, were recorded and analyzed using a walking track equipped with a video-based system. Expression of substance P (SP), calcitonin gene related peptide (CGRP), and galanin were used as pain markers. Beta-III tubulin and Masson trichrome staining were used as to evaluate nerve sprouting, matrix tension, and degeneration in the tendon. Of fourteen analyzed parameters, RF significantly improved stance phase, step length, preswing, and intermediary toe-spread of gait. Improved gait related to the expression of substance P, CGRP, and reduced nerve fiber sprouting and matrix tension, but not galanin. The study indicates that direct RF application may be a valuable approach to improve gait and pain in acute tendon injury. Altered gait parameters may be used as references to evaluate therapeutic outcomes of RF or other treatment plan for tendinopathy.
format Online
Article
Text
id pubmed-3853797
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-38537972013-12-12 Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury Tsai, Yun-Pu Chang, Chi-Wen Lee, Jung-Shun Liang, Jen-I Hsieh, Tsung-Hsun Yeh, Ming-Long Sze, Chun-I Evid Based Complement Alternat Med Research Article Radiofrequency (RF) is often used as a supplementary and alternative method to alleviate pain for chronic tendinopathy. Whether or how it would work for acute tendon injury is not addressed in the literatures. Through detailed pain and gait monitoring, we hypothesized that collagenase-induce acute tendinopathy model may be able to answer these questions. Gait parameters, including time, distance, and range of motion, were recorded and analyzed using a walking track equipped with a video-based system. Expression of substance P (SP), calcitonin gene related peptide (CGRP), and galanin were used as pain markers. Beta-III tubulin and Masson trichrome staining were used as to evaluate nerve sprouting, matrix tension, and degeneration in the tendon. Of fourteen analyzed parameters, RF significantly improved stance phase, step length, preswing, and intermediary toe-spread of gait. Improved gait related to the expression of substance P, CGRP, and reduced nerve fiber sprouting and matrix tension, but not galanin. The study indicates that direct RF application may be a valuable approach to improve gait and pain in acute tendon injury. Altered gait parameters may be used as references to evaluate therapeutic outcomes of RF or other treatment plan for tendinopathy. Hindawi Publishing Corporation 2013 2013-11-20 /pmc/articles/PMC3853797/ /pubmed/24348697 http://dx.doi.org/10.1155/2013/402692 Text en Copyright © 2013 Yun-Pu Tsai et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tsai, Yun-Pu
Chang, Chi-Wen
Lee, Jung-Shun
Liang, Jen-I
Hsieh, Tsung-Hsun
Yeh, Ming-Long
Sze, Chun-I
Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title_full Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title_fullStr Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title_full_unstemmed Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title_short Direct Radiofrequency Application Improves Pain and Gait in Collagenase-Induced Acute Achilles Tendon Injury
title_sort direct radiofrequency application improves pain and gait in collagenase-induced acute achilles tendon injury
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853797/
https://www.ncbi.nlm.nih.gov/pubmed/24348697
http://dx.doi.org/10.1155/2013/402692
work_keys_str_mv AT tsaiyunpu directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT changchiwen directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT leejungshun directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT liangjeni directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT hsiehtsunghsun directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT yehminglong directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury
AT szechuni directradiofrequencyapplicationimprovespainandgaitincollagenaseinducedacuteachillestendoninjury