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Transcriptional regulation and its misregulation in Alzheimer’s disease
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by loss of memory and cognitive function. A key neuropathological event in AD is the accumulation of amyloid-β (Aβ) peptide. The production and clearance of Aβ in the brain are regulated by a large group of genes. The...
Autores principales: | Chen, Xiao-Fen, Zhang, Yun-wu, Xu, Huaxi, Bu, Guojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854070/ https://www.ncbi.nlm.nih.gov/pubmed/24144318 http://dx.doi.org/10.1186/1756-6606-6-44 |
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