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Determination of periodontopathogens in patients with Cri du chat syndrome

Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in...

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Autores principales: Ballesta-Mudarra, Sofía, Machuca-Portillo, Guillermo, Torres-Lagares, Daniel, Rodríguez-Caballero, Ángela, Yáñez-Vico, Rosa M., Solano-Reina, Enrique, Perea-Pérez, Evelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854081/
https://www.ncbi.nlm.nih.gov/pubmed/24121919
http://dx.doi.org/10.4317/medoral.19400
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author Ballesta-Mudarra, Sofía
Machuca-Portillo, Guillermo
Torres-Lagares, Daniel
Rodríguez-Caballero, Ángela
Yáñez-Vico, Rosa M.
Solano-Reina, Enrique
Perea-Pérez, Evelio
author_facet Ballesta-Mudarra, Sofía
Machuca-Portillo, Guillermo
Torres-Lagares, Daniel
Rodríguez-Caballero, Ángela
Yáñez-Vico, Rosa M.
Solano-Reina, Enrique
Perea-Pérez, Evelio
author_sort Ballesta-Mudarra, Sofía
collection PubMed
description Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Key words:Cri du Chat syndrome, periodontal health, microbiology, special care dentistry.
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spelling pubmed-38540812013-12-09 Determination of periodontopathogens in patients with Cri du chat syndrome Ballesta-Mudarra, Sofía Machuca-Portillo, Guillermo Torres-Lagares, Daniel Rodríguez-Caballero, Ángela Yáñez-Vico, Rosa M. Solano-Reina, Enrique Perea-Pérez, Evelio Med Oral Patol Oral Cir Bucal Research-Article Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Key words:Cri du Chat syndrome, periodontal health, microbiology, special care dentistry. Medicina Oral S.L. 2013-11 2013-10-13 /pmc/articles/PMC3854081/ /pubmed/24121919 http://dx.doi.org/10.4317/medoral.19400 Text en Copyright: © 2013 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research-Article
Ballesta-Mudarra, Sofía
Machuca-Portillo, Guillermo
Torres-Lagares, Daniel
Rodríguez-Caballero, Ángela
Yáñez-Vico, Rosa M.
Solano-Reina, Enrique
Perea-Pérez, Evelio
Determination of periodontopathogens in patients with Cri du chat syndrome
title Determination of periodontopathogens in patients with Cri du chat syndrome
title_full Determination of periodontopathogens in patients with Cri du chat syndrome
title_fullStr Determination of periodontopathogens in patients with Cri du chat syndrome
title_full_unstemmed Determination of periodontopathogens in patients with Cri du chat syndrome
title_short Determination of periodontopathogens in patients with Cri du chat syndrome
title_sort determination of periodontopathogens in patients with cri du chat syndrome
topic Research-Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854081/
https://www.ncbi.nlm.nih.gov/pubmed/24121919
http://dx.doi.org/10.4317/medoral.19400
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