Cargando…

Protective effect of the APOE-e3 allele in Alzheimer's disease

Although several alleles of susceptibility to Alzheimer's disease (AD) have been studied in the last decades, few polymorphisms have been considered as risk factors for the disease. Among them, the APOE-e4 allele appears to be the major genetic risk factor for the onset of the disease. However,...

Descripción completa

Detalles Bibliográficos
Autores principales:	de-Almada, B.V.P., de-Almeida, L.D., Camporez, D., de-Moraes, M.V.D., Morelato, R.L., Perrone, A.M.S., Belcavello, L., Louro, I.D., de-Paula, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Medicina Tropical 2011
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854133/ https://www.ncbi.nlm.nih.gov/pubmed/22068907 http://dx.doi.org/10.1590/S0100-879X2011007500151

Ejemplares similares

The combined risk effect among BIN1, CLU, and APOE genes in Alzheimer’s disease
por: dos Santos, Lígia Ramos, et al.
Publicado: (2020)

Polygenic Risk Score Analysis of Alzheimer’s Disease in Cases without APOE4 or APOE2 Alleles
por: Escott-Price, V., et al.
Publicado: (2018)

APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease
por: Yassine, Hussein N., et al.
Publicado: (2020)

APOE ε4, an Alzheimer’s disease susceptibility allele, and smoking cessation
por: Ashare, Rebecca L., et al.
Publicado: (2012)

THE APOE-ε4 ALLELE AND AGE SYNERGISTICALLY DRIVE DISEASE PROGRESSION IN ALZHEIMER’S DISEASE
por: Kleineidam, Luca, et al.
Publicado: (2019)

APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease
por: Vélez, J I, et al.
Publicado: (2016)

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis
por: Madrid, Laura, et al.
Publicado: (2021)

Apo E4 Alleles and Impaired Olfaction as Predictors of Alzheimer’s Disease
por: Misiak, Magdalena M, et al.
Publicado: (2017)

APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer’s Disease
por: Hohman, Timothy J., et al.
Publicado: (2017)

Breast Cancer, Alzheimer’s Disease, and APOE4 Allele in the UK Biobank Cohort
por: Lehrer, Steven, et al.
Publicado: (2021)

Relationship between the Presence of the ApoE ε4 Allele and EEG Complexity along the Alzheimer’s Disease Continuum
por: Gutiérrez-de Pablo, Víctor, et al.
Publicado: (2020)

Murine Gut Microbiome Association With APOE Alleles
por: Parikh, Ishita J., et al.
Publicado: (2020)

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
por: Walker, Rosie M., et al.
Publicado: (2021)

Association of the C47T Polymorphism in SOD2 with Amnestic Mild Cognitive Impairment and Alzheimer's Disease in Carriers of the APOEε4 Allele
por: Gamarra, David, et al.
Publicado: (2015)

Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele
por: Padayachee, E.R., et al.
Publicado: (2016)

Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice
por: Moser, V. Alexandra, et al.
Publicado: (2017)

Obesity reduces hippocampal structure and function in older African Americans with the APOE-ε4 Alzheimer’s disease risk allele
por: Osiecka, Zuzanna, et al.
Publicado: (2023)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
por: Soyal, Selma M., et al.
Publicado: (2020)

Characterization of APOE and TOMM40 allele frequencies in the Japanese population
por: Nishimura, Akira, et al.
Publicado: (2017)

Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies
por: Goldberg, Terry E., et al.
Publicado: (2020)

A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers
por: Ayers, Kristin L., et al.
Publicado: (2016)

Effect of APOE ε4 allele on survival and fertility in an adverse environment
por: van Exel, Eric, et al.
Publicado: (2017)

The Role of Upregulated APOE in Alzheimer’s Disease Etiology
por: Gottschalk, William K, et al.
Publicado: (2016)

Association between the APOE ε4 Allele and Late-Onset Alzheimer's Disease in an Ecuadorian Mestizo Population
por: Montufar, Stefany, et al.
Publicado: (2017)

APOE ε4 Allele Is Associated with Elevated Levels of CSF VILIP-1 in Preclinical Alzheimer’s Disease
por: Wang, Lijun, et al.
Publicado: (2020)

APOE ɛ4 Allele and Financial Capacity Performance in Mild Alzheimer’s Disease: A Pilot Study
por: Giannouli, Vaitsa, et al.
Publicado: (2021)

Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
por: Kulminski, Alexander M., et al.
Publicado: (2022)

APOE effects on regional tau in preclinical Alzheimer’s disease
por: Young, Christina B., et al.
Publicado: (2023)

A polygenic risk score for Alzheimer’s disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S.
por: Sofer, Tamar, et al.
Publicado: (2023)

Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise
por: Jensen, Camilla Steen, et al.
Publicado: (2019)

APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer’s disease and related dementia
por: Savignac, Chloé, et al.
Publicado: (2022)

ApoE Modifier Alleles for Alzheimer's Disease Discovered by Information Theory Dependency Measures: MIST Software Package
por: Banman, Andrew, et al.
Publicado: (2023)

Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis
por: Abdullah, L, et al.
Publicado: (2023)

APOE genotype and Alzheimer’s immunotherapy
por: Pankiewicz, Joanna E., et al.
Publicado: (2017)

ApoE4: an emerging therapeutic target for Alzheimer’s disease
por: Safieh, Mirna, et al.
Publicado: (2019)

Cognitive and neural signatures of the APOE E4 allele in mid-aged adults
por: Evans, Simon, et al.
Publicado: (2014)

DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health
por: Mur, Jure, et al.
Publicado: (2020)

APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans
por: Yu, Lei, et al.
Publicado: (2017)

APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
por: Stephen, T. L., et al.
Publicado: (2019)

Dissecting the Gene Dose-Effects of the APOE ε4 and ε2 Alleles on Hippocampal Volumes in Aging and Alzheimer’s Disease
por: Hostage, Christopher A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o9slg502d6dg8ij492b1uads9u