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Evaluation of chromosomal abnormalities by clg-FISH and association with proliferative and apoptotic indexes in multiple myeloma

Eighty-six newly diagnosed multiple myeloma (MM) patients from a public hospital of São Paulo (Brazil) were evaluated by cIg-FISH for the presence of del(13)(q14), t(4;14)(p16.3;q32) and del(17)(p13). These abnormalities were observed in 46.5, 9.3, and 7.0% of the patients, respectively. In order to...

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Detalles Bibliográficos
Autores principales: Linardi, C.C.G., Martinez, G., Velloso, E.D.R.P., Leal, A.M., Kumeda, C.A., Buccheri, V., Azevedo, R.S., Peliçario, L.M., Dorlhiac-Llacer, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854150/
https://www.ncbi.nlm.nih.gov/pubmed/22911347
http://dx.doi.org/10.1590/S0100-879X2012007500135

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