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The role of Ca(2+)/calmodulin-dependent protein kinase II and calcineurin in TNF-α-induced myocardial hypertrophy

We investigated whether Ca(2+)/calmodulin-dependent kinase II (CaMKII) and calcineurin (CaN) are involved in myocardial hypertrophy induced by tumor necrosis factor α (TNF-α). The cardiomyocytes of neonatal Wistar rats (1-2 days old) were cultured and stimulated by TNF-α (100 µg/L), and Ca(2+) signa...

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Detalles Bibliográficos
Autores principales:	Wang, Gui-Jun, Wang, Hong-Xin, Yao, Yu-Sheng, Guo, Lian-Yi, Liu, Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Medicina Tropical 2012
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854156/ https://www.ncbi.nlm.nih.gov/pubmed/22832601 http://dx.doi.org/10.1590/S0100-879X2012007500121

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