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Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin

Animal models of gentamicin nephrotoxicity present acute tubular necrosis associated with inflammation, which can contribute to intensify the renal damage. Hydrogen sulfide (H(2)S) is a signaling molecule involved in inflammation. We evaluated the effect of DL-propargylglycine (PAG), an inhibitor of...

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Detalles Bibliográficos
Autores principales: Francescato, H.D.C., Chierice, J.R.A., Marin, E.C.S., Cunha, F.Q., Costa, R.S., Silva, C.G.A., Coimbra, T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854203/
https://www.ncbi.nlm.nih.gov/pubmed/22331137
http://dx.doi.org/10.1590/S0100-879X2012007500016

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