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p16 (INK4a) has clinicopathological and prognostic impact on oropharynx and larynx squamous cell carcinoma
CDKN2A encodes proteins such as p16 (INK4a), which negatively regulate the cell-cycle. Molecular genetic studies have revealed that deletions in CDKN2A occur frequently in cancer. Although p16 (INK4a) may be involved in tumor progression, the clinical impact and prognostic implications in head and n...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Medicina Tropical
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854204/ https://www.ncbi.nlm.nih.gov/pubmed/22948376 http://dx.doi.org/10.1590/S0100-879X2012007500140 |