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2-Bromo-1,4-naphthoquinone: a potentially improved substitute of menadione in Apatone™ therapy

Apatone™, a combination of menadione (2-methyl-1,4-naphthoquinone, VK(3)) and ascorbic acid (vitamin C, VC) is a new strategy for cancer treatment. Part of its effect on tumor cells is related to the cellular pro-oxidative imbalance provoked by the generation of hydrogen peroxide (H(2)O(2)) through...

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Detalles Bibliográficos
Autores principales:	Graciani, F.S., Ximenes, V.F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Medicina Tropical 2012
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854242/ https://www.ncbi.nlm.nih.gov/pubmed/22584645 http://dx.doi.org/10.1590/S0100-879X2012007500078

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