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Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology
Vaccine development faces major difficulties partly because of genetic variation in both infectious organisms and humans. This causes antigenic variation in infectious agents and a high interindividual variability in the human response to the vaccine. The exponential growth of genome sequence inform...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Medicina Tropical
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854287/ https://www.ncbi.nlm.nih.gov/pubmed/22030866 http://dx.doi.org/10.1590/S0100-879X2011007500142 |