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Adenovirus-mediated siRNA targeting TNF-α and overexpression of bone morphogenetic protein-2 promotes early osteoblast differentiation on a cell model of Ti particle-induced inflammatory response in vitro

Wear particles are phagocytosed by macrophages and other inflammatory cells, resulting in cellular activation and release of proinflammatory factors, which cause periprosthetic osteolysis and subsequent aseptic loosening, the most common causes of total joint arthroplasty failure. During this pathol...

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Detalles Bibliográficos
Autores principales:	Guo, H.H., Yu, C.C., Sun, S.X., Ma, X.J., Yang, X.C., Sun, K.N., Jin, Q.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2013
Materias:	Biomedical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854310/ https://www.ncbi.nlm.nih.gov/pubmed/24141610 http://dx.doi.org/10.1590/1414-431X20133092

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