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The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells

Epigenetic mechanisms such as DNA methylation and histone modification are important in stem cell differentiation. Methylation is principally associated with transcriptional repression, and histone acetylation is correlated with an active chromatin state. We determined the effects of these epigeneti...

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Detalles Bibliográficos
Autores principales:	Zych, J., Stimamiglio, M.A., Senegaglia, A.C., Brofman, P.R.S., Dallagiovanna, B., Goldenberg, S., Correa, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2013
Materias:	Biomedical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854397/ https://www.ncbi.nlm.nih.gov/pubmed/23797495 http://dx.doi.org/10.1590/1414-431X20132893

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