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H(1) but not H(2) histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing

This study investigated the role of H(1) and H(2) receptors in anxiety and the retrieval of emotional memory using a Trial 1/Trial 2 (T1/T2) protocol in an elevated plus-maze (EPM). Tests were performed on 2 consecutive days, designated T1 and T2. Before T1, the mice received intraperitoneal injecti...

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Detalles Bibliográficos
Autores principales: Serafim, K.R., Kishi, M.S., Canto-de-Souza, A., Mattioli, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854398/
https://www.ncbi.nlm.nih.gov/pubmed/23598647
http://dx.doi.org/10.1590/1414-431X20132770