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ROCS: A reproducibility index and confidence score for interaction proteomics

Background Affinity-Purification Mass-Spectrometry (AP-MS) provides a powerful means of identifying protein complexes and interactions. Several important challenges exist in interpreting the results of AP-MS experiments. First, the reproducibility of AP-MS experimental replicates can be low, due bot...

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Detalles Bibliográficos
Autores principales: Kabagenyi, Allen, Ndugga, Patricia, Wandera, Stephen OJIAMBO, Kwagala, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854487/
https://www.ncbi.nlm.nih.gov/pubmed/24156626
http://dx.doi.org/10.1186/1471-2458-13-1009