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Conserved-residue mutations in Wzy affect O-antigen polymerization and Wzz-mediated chain-length regulation in Pseudomonas aeruginosa PAO1

O antigen (O-Ag) in many bacteria is synthesized via the Wzx/Wzy-dependent pathway in which Wzy polymerizes lipid-linked O-Ag subunits to modal lengths regulated by Wzz. Characterization of 83 site-directed mutants of Wzy from Pseudomonas aeruginosa PAO1 (Wzy(Pa)) in topologically-mapped periplasmic...

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Detalles Bibliográficos
Autores principales:	Islam, Salim T., Huszczynski, Steven M., Nugent, Timothy, Gold, Alexander C., Lam, Joseph S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854497/ https://www.ncbi.nlm.nih.gov/pubmed/24309320 http://dx.doi.org/10.1038/srep03441

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