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Understanding Variation in Transcription Factor Binding by Modeling Transcription Factor Genome-Epigenome Interactions

Despite explosive growth in genomic datasets, the methods for studying epigenomic mechanisms of gene regulation remain primitive. Here we present a model-based approach to systematically analyze the epigenomic functions in modulating transcription factor-DNA binding. Based on the first principles of...

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Detalles Bibliográficos
Autores principales:	Chen, Chieh-Chun, Xiao, Shu, Xie, Dan, Cao, Xiaoyi, Song, Chun-Xiao, Wang, Ting, He, Chuan, Zhong, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854512/ https://www.ncbi.nlm.nih.gov/pubmed/24339764 http://dx.doi.org/10.1371/journal.pcbi.1003367

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