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Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways

Nonsense-mediated mRNA decay (NMD) is a eukaryotic post-transcriptional gene regulation mechanism that eliminates mRNAs with the termination codon (TC) located in an unfavorable environment for efficient translation termination. The best-studied NMD-targeted mRNAs contain premature termination codon...

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Detalles Bibliográficos
Autores principales:	Metze, Stefanie, Herzog, Veronika A., Ruepp, Marc-David, Mühlemann, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854533/ https://www.ncbi.nlm.nih.gov/pubmed/23962664 http://dx.doi.org/10.1261/rna.038893.113

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