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A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction

The current treatment regimens for HIV include over 20 anti-retrovirals. However, adverse drug effects and the emergence of drug resistance necessitates the continued improvement of the existing drug classes as well as the development of novel drugs that target as yet therapeutically unexploited vir...

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Detalles Bibliográficos
Autores principales:	Breuer, Sebastian, Espinola, Sheryll, Morelli, Xavier, Torbett, Bruce E, Arold, Stefan T, Engels, Ingo H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854662/ https://www.ncbi.nlm.nih.gov/pubmed/24396731 http://dx.doi.org/10.2174/2213988501307010016

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