Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectives

Heart diseases remain a major cause of mortality and morbidity worldwide. However, terminally differentiated human adult cardiomyocytes (CMs) possess a very limited innate ability to regenerate. Directed differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs)...

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Detalles Bibliográficos
Autores principales: Chow, Maggie Zi, Boheler, Kenneth R, Li, Ronald A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854712/
https://www.ncbi.nlm.nih.gov/pubmed/23953772
http://dx.doi.org/10.1186/scrt308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854712/
https://www.ncbi.nlm.nih.gov/pubmed/23953772
http://dx.doi.org/10.1186/scrt308

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