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Synergistic effect of Indian hedgehog and bone morphogenetic protein-2 gene transfer to increase the osteogenic potential of human mesenchymal stem cells

INTRODUCTION: To stimulate healing of large bone defects research has concentrated on the application of mesenchymal stem cells (MSCs). METHODS: In the present study, we induced the overexpression of the growth factors bone morphogenetic protein 2 (BMP-2) and/or Indian hedgehog (IHH) in human MSCs b...

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Detalles Bibliográficos
Autores principales:	Reichert, Johannes C, Schmalzl, Jonas, Prager, Patrick, Gilbert, Fabian, Quent, Verena MC, Steinert, Andre F, Rudert, Maximilian, Nöth, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854715/ https://www.ncbi.nlm.nih.gov/pubmed/24004723 http://dx.doi.org/10.1186/scrt316

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