Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

INTRODUCTION: Huntington’s disease (HD) is an autosomal dominant disorder caused by an expanded CAG repeat on the short arm of chromosome 4 resulting in cognitive decline, motor dysfunction, and death, typically occurring 15 to 20 years after the onset of motor symptoms. Neuropathologically, HD is c...

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Detalles Bibliográficos
Autores principales: Fink, Kyle D, Rossignol, Julien, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Bavar, Angela M, Clerc, Steven, Lowrance, Steven A, Song, Cheng, Lescaudron, Laurent, Dunbar, Gary L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854759/
https://www.ncbi.nlm.nih.gov/pubmed/24456799
http://dx.doi.org/10.1186/scrt341

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