Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo

Loss of function mutations of Kif7, the vertebrate orthologue of the Drosophila Hh pathway component Costal2, cause defects in the limbs and neural tubes of mice, attributable to ectopic expression of Hh target genes. While this implies a functional conservation of Cos2 and Kif7 between flies and ve...

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Detalles Bibliográficos
Autores principales: Maurya, Ashish Kumar, Ben, Jin, Zhao, Zhonghua, Lee, Raymond Teck Ho, Niah, Weixin, Ng, Ashley Shu Mei, Iyu, Audrey, Yu, Weimiao, Elworthy, Stone, van Eeden, Fredericus J. M., Ingham, Philip William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854788/
https://www.ncbi.nlm.nih.gov/pubmed/24339784
http://dx.doi.org/10.1371/journal.pgen.1003955

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