Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis

Development in the central nervous system is highly dependent on the regulation of the switch from progenitor cell proliferation to differentiation, but the molecular and cellular events controlling this process remain poorly understood. Here, we report that ablation of Crb1 and Crb2 genes results i...

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Detalles Bibliográficos
Autores principales: Pellissier, Lucie P., Alves, Celso Henrique, Quinn, Peter M., Vos, Rogier M., Tanimoto, Naoyuki, Lundvig, Ditte M. S., Dudok, Jacobus J., Hooibrink, Berend, Richard, Fabrice, Beck, Susanne C., Huber, Gesine, Sothilingam, Vithiyanjali, Garcia Garrido, Marina, Le Bivic, André, Seeliger, Mathias W., Wijnholds, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854796/
https://www.ncbi.nlm.nih.gov/pubmed/24339791
http://dx.doi.org/10.1371/journal.pgen.1003976

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