Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase

Exit from mitosis in budding yeast is triggered by activation of the key mitotic phosphatase Cdc14. At anaphase onset, the protease separase and Zds1 promote the downregulation of PP2A(Cdc55) phosphatase, which facilitates Cdk1-dependent phosphorylation of Net1 and provides the first wave of Cdc14 a...

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Detalles Bibliográficos
Autores principales: Baro, Barbara, Rodriguez-Rodriguez, Jose-Antonio, Calabria, Ines, Hernáez, María Luisa, Gil, Concha, Queralt, Ethel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854864/
https://www.ncbi.nlm.nih.gov/pubmed/24339788
http://dx.doi.org/10.1371/journal.pgen.1003966

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