Soulamarin Isolated from Calophyllum brasiliense (Clusiaceae) Induces Plasma Membrane Permeabilization of Trypanosoma cruzi and Mytochondrial Dysfunction

Chagas disease is caused by the parasitic protozoan Trypanosoma cruzi. It has high mortality as well as morbidity rates and usually affects the poorer sections of the population. The development of new, less harmful and more effective drugs is a promising research target, since current standard trea...

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Detalles Bibliográficos
Autores principales: Rea, Alexandre, Tempone, Andre G., Pinto, Erika G., Mesquita, Juliana T., Rodrigues, Eliana, Silva, Luciana Grus M., Sartorelli, Patricia, Lago, João Henrique G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854968/
https://www.ncbi.nlm.nih.gov/pubmed/24340110
http://dx.doi.org/10.1371/journal.pntd.0002556

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