A Trifunctional Dextran-Based Nanovaccine Targets and Activates Murine Dendritic Cells, and Induces Potent Cellular and Humoral Immune Responses In Vivo

Dendritic cells (DCs) constitute an attractive target for specific delivery of nanovaccines for immunotherapeutic applications. Here we tested nano-sized dextran (DEX) particles to serve as a DC-addressing nanocarrier platform. Non-functionalized DEX particles had no immunomodulatory effect on bone...

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Detalles Bibliográficos
Autores principales: Shen, Limei, Higuchi, Tetsuya, Tubbe, Ingrid, Voltz, Nicole, Krummen, Mathias, Pektor, Stefanie, Montermann, Evelyn, Rausch, Kristin, Schmidt, Manfred, Schild, Hansjörg, Grabbe, Stephan, Bros, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855172/
https://www.ncbi.nlm.nih.gov/pubmed/24339889
http://dx.doi.org/10.1371/journal.pone.0080904

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