A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4

Prostate cancer (PCa) is the second highest cause of cancer death in United States males. If the metastatic movement of PCa cells could be inhibited, then mortality from PCa could be greatly reduced. Mitogen-activated protein kinase kinase 4 (MAP2K4) has previously been shown to activate pro-invasio...

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Detalles Bibliográficos
Autores principales: Krishna, Sankar N., Luan, Chi-Hao, Mishra, Rama K., Xu, Li, Scheidt, Karl A., Anderson, Wayne F., Bergan, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855329/
https://www.ncbi.nlm.nih.gov/pubmed/24339940
http://dx.doi.org/10.1371/journal.pone.0081504

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