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HNRNPA1 interacts with a 5′ flanking distal element of interleukin 6 and up-regulates its basal transcription
Interleukin-6 (IL-6) is an important pro-inflammatory cytokine involved in many autoimmune and inflammatory diseases. We have shown previously that a region from −5307 to −5202 bp upstream of the IL-6 transcriptional start site is responsible for basal IL-6 gene expression and that there were DNA bi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855448/ https://www.ncbi.nlm.nih.gov/pubmed/23985572 http://dx.doi.org/10.1038/gene.2013.41 |