Multisite phosphorylation networks as signal processors for Cdk1

The order and timing of cell cycle events is controlled by changing substrate specificity and different activity thresholds of cyclin-dependent kinases (CDK). However, it is not understood how a single protein kinase can trigger hundreds of switches in a sufficiently time-resolved fashion. We show t...

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Detalles Bibliográficos
Autores principales: Kõivomägi, Mardo, Örd, Mihkel, Iofik, Anna, Valk, Ervin, Venta, Rainis, Faustova, Ilona, Kivi, Rait, Balog, Eva Rose M., Rubin, Seth M., Loog, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855452/
https://www.ncbi.nlm.nih.gov/pubmed/24186061
http://dx.doi.org/10.1038/nsmb.2706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855452/
https://www.ncbi.nlm.nih.gov/pubmed/24186061
http://dx.doi.org/10.1038/nsmb.2706

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