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Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model

Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS) is an adult-onset neuromuscular degenerative disorder...

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Detalles Bibliográficos
Autores principales: Luo, Guo, Yi, Jianxun, Ma, Changling, Xiao, Yajuan, Yi, Frank, Yu, Tian, Zhou, Jingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855744/
https://www.ncbi.nlm.nih.gov/pubmed/24324755
http://dx.doi.org/10.1371/journal.pone.0082112