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Defective Mitochondrial Dynamics Is an Early Event in Skeletal Muscle of an Amyotrophic Lateral Sclerosis Mouse Model
Mitochondria are dynamic organelles that constantly undergo fusion and fission to maintain their normal functionality. Impairment of mitochondrial dynamics is implicated in various neurodegenerative disorders. Amyotrophic lateral sclerosis (ALS) is an adult-onset neuromuscular degenerative disorder...
Autores principales: | Luo, Guo, Yi, Jianxun, Ma, Changling, Xiao, Yajuan, Yi, Frank, Yu, Tian, Zhou, Jingsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855744/ https://www.ncbi.nlm.nih.gov/pubmed/24324755 http://dx.doi.org/10.1371/journal.pone.0082112 |
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