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Glycosylation of Immunoglobulin G: Role of Genetic and Epigenetic Influences

OBJECTIVE: To determine the extent to which genetic and epigenetic factors contribute to variations in glycosylation of immunoglobulin G (IgG) in humans. METHODS: 76 N-glycan traits in circulating IgG were analyzed by UPLC in 220 monozygotic and 310 dizygotic twin pairs from TwinsUK. A classical tw...

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Detalles Bibliográficos
Autores principales:	Menni, Cristina, Keser, Toma, Mangino, Massimo, Bell, Jordana T., Erte, Idil, Akmačić, Irena, Vučković, Frano, Pučić Baković, Maja, Gornik, Olga, McCarthy, Mark I., Zoldoš, Vlatka, Spector, Tim D., Lauc, Gordan, Valdes, Ana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855797/ https://www.ncbi.nlm.nih.gov/pubmed/24324808 http://dx.doi.org/10.1371/journal.pone.0082558

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