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Racial Difference in Human Platelet PAR4 Reactivity Reflects Expression of PCTP and miR-376c
Racial differences in the pathophysiology of atherothrombosis are poorly understood. We explored the function and transcriptome of platelets in healthy black (n = 70) and white (n = 84) subjects. PAR4 thrombin receptor induced platelet aggregation and calcium mobilization were significantly greater...
Autores principales: | Edelstein, Leonard C., Simon, Lukas M., Montoya, Raúl Teruel, Holinstat, Michael, Chen, Edward S., Bergeron, Angela, Kong, Xianguo, Nagalla, Srikanth, Mohandas, Narla, Cohen, David E., Dong, Jing-fei, Shaw, Chad, Bray, Paul F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855898/ https://www.ncbi.nlm.nih.gov/pubmed/24216752 http://dx.doi.org/10.1038/nm.3385 |
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