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Hyperoxia Exacerbates Postnatal Inflammation-Induced Lung Injury in Neonatal BRP-39 Null Mutant Mice Promoting the M1 Macrophage Phenotype

Rationale. Hyperoxia exposure to developing lungs—critical in the pathogenesis of bronchopulmonary dysplasia—may augment lung inflammation by inhibiting anti-inflammatory mediators in alveolar macrophages. Objective. We sought to determine the O(2)-induced effects on the polarization of macrophages...

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Detalles Bibliográficos
Autores principales: Syed, Mansoor A., Bhandari, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855965/
https://www.ncbi.nlm.nih.gov/pubmed/24347826
http://dx.doi.org/10.1155/2013/457189